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Factbox: Latest on the worldwide spread of the coronavirus

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(Reuters) - A Reuters tally showed new U.S. COVID-19 cases rose by nearly 50,000 on Wednesday, the biggest one-day spike on record, a day after the government's top infectious diseases expert warned that daily cases could double to 100,000 if the necessary steps were not taken.

DEATHS AND INFECTIONS

* For an interactive graphic tracking the global spread, open https://tmsnrt.rs/3aIRuz7 in an external browser.

* For a U.S.-focused tracker with state-by-state and county map, open https://tmsnrt.rs/2w7hX9T in an external browser.

* Eikon users, see MacroVitals (cpurl://apps.cp./cms/?navid=1592404098) for a case tracker and a summary of developments.

AMERICAS

* Governors of U.S. states hit hardest by the resurgent virus cases halted or reversed steps to reopen their economies, led by the nation's most populous state California.

* Brazil's death toll crossed 60,000, with the governor of Sao Paulo state saying that a potential vaccine developed by China's Sinovac will be tested by 12 research centres in six Brazilian states.

* Colombia's national COVID-19 tally surpassed 100,000 cases, while Mexico's death toll exceeded Spain's total number of fatalities from the virus.

ASIA-PACIFIC

* Australian police set up suburban checkpoints in hotspots in Melbourne and were considering using drones to enforce stay-at-home orders.

* India's infections crossed 600,000 on Thursday, with 17,834 deaths.

MIDDLE EAST AND AFRICA

* Israel's parliament voted on Wednesday to allow the country's domestic intelligence agency to track cellphones of COVID-19 carriers for the next three weeks.

* Nigeria will resume domestic flights from July 8.

EUROPE

* The British government will outline plans for air bridges later this week that will allow people to go on holiday to certain countries without facing quarantine on their return.

* Spain and Portugal officially reopened their joint border to all travellers after a three-month closure.

MEDICAL DEVELOPMENTS

* A vaccine developed by German biotech firm BioNTech and U.S. pharmaceutical giant Pfizer has shown potential and was found to be well tolerated in early-stage human trials.

* A leading scientist behind the University of Oxford's potential COVID-19 vaccine said the team has seen the right sort of immune response in trials but declined to give a firm time frame for when it could be ready.

* Japan's Fujifilm announced a deal with India's Dr Reddy's and Dubai-based Global Response Aid to sell its anti-flu drug Avigan for COVID-19 treatment globally excluding Japan, China and Russia.

ECONOMIC FALLOUT

* Asian stocks tracked Wall Street higher although sentiment was cautious ahead of U.S. employment data, while copper prices jumped to more than six-month highs on a better global outlook and supply fears in top producer Chile.

* St. Louis Federal Reserve president James Bullard told the Financial Times that a wave of "substantial bankruptcies" triggered by the pandemic could lead to a financial crisis.

* Global tourism revenues are expected to fall by up to $3.3 trillion, with the United States standing to lose the most, according to a U.N. study.

(Compiled by Aditya Soni, Anita Kobylinska and Linda Pasquini; Edited by Shounak Dasgupta and Sriraj Kalluvila)

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